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Latest from Actorius

Explore the latest updates, research perspectives, announcements, and stories shaping our work.

CTCs as biomarkers for relapse detection in rectal cancer with liver metastasis.
29 Jun 2024

Manuscript: Circulating Tumor Cells as Biomarkers for Relapse Detection in Rectal Cancer with Liver Metastasis: Insights from a Case Report

In this case report we demonstrate the utility of CTC as a sensitive marker to detect MRD. CTCs play a crucial role in the context of MRD in colorectal cancer, offering a valuable biomarker for prognosis, treatment monitoring, and early detection of recurrence.

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ASCO 2024 | Actorius Innovations and Research
4 Jun 2024

ASCO 2024: Effect of circulating tumor cells in clinically stable patients on the conundrum of recurrence with cellular residual disease.

CTC detection with PD-L1 expression reveals residual disease despite negative radiological findings in treated cancer patients.

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ASCO 2024 | Actorius Innovations and Research
3 Jun 2024

ASCO 2024: Effect of circulating tumor cells (CTC) and CTC clusters with PD-L1 dynamic biomarker on cellular burden in patients with ovarian cancer.

CTCs with PD-L1 expression in ovarian cancer reveal minimal residual disease and may guide immunotherapy and early metastasis monitoring.

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ASCO 2024 | Actorius Innovations and Research
3 Jun 2024

ASCO 2024: Measure of minimal residual burden on CTCs with over-expression of PD-L1 as a dynamic biomarker in patients with colorectal cancer.

CTC detection with PD-L1 expression in colorectal cancer reveals minimal residual disease and supports personalized treatment strategies.

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ASCO 2024 | Actorius Innovations and Research
3 Jun 2024

ASCO 2024: Impact of ctDNA genomic mutations and CTCs biomarker duo on clinical concordance in localized, progressive, and metastatic disease.

Dual biomarker analysis of ctDNA and circulating tumor cells reveals disease progression and metastasis across multiple cancer types.

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ASCO 2024 | Actorius Innovations and Research
3 Jun 2024

ASCO 2024: Association of complementing ctDNA and CTCs load on stable and progressive disease in treated patients.

Complementary ctDNA and CTC biomarkers reveal minimal residual disease and predict cancer progression after curative-intent treatment.

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Nature India | Actorius Innovations and Research
11 Apr 2024

Magnetic nanocrystals capture tumour cells from blood samples

These nanomaterials could speed up discovery of anti-cancer drugs

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AACR 2024 | Actorius Innovations and Research
10 Apr 2024

AACR 2024: Distribution prophecy of circulating tumor cell clusters in CTC populace patients of epithelial cancers

Large-scale analysis of circulating tumor cells and clusters reveals their role in predicting aggressive epithelial cancers and treatment resistance.

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AACR 2024 | Actorius Innovations and Research
10 Apr 2024

AACR 2024: Evaluation of HER-2 expression on circulating tumor cells as a real time biomarker in advanced breast cancer

HER2 analysis on circulating tumor cells using the OncoDiscover® platform enables real-time, non-invasive profiling for improved metastatic breast cancer treatment decisions.

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CTC together with Shh and Nrf2 are prospective diagnostic markers for HNSCC
4 Apr 2024

Manuscript: CTC together with Shh and Nrf2 are prospective diagnostic markers for HNSCC

Study links Shh/Nrf2 overexpression with circulating tumor cells in HNSCC, highlighting their potential as biomarkers for early detection and survival prediction.

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ESMO 2023 | Actorius Innovations and Research
24 Oct 2023

ESMO 2023: Expression of PD-L1 and EGFR on circulating tumor cells in advanced Lung cancer patients

CTC analysis using OncoDiscover® enables dynamic detection of PD-L1 and EGFR targets in advanced lung cancer, supporting personalized targeted and immunotherapy decisions.

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Magnetically activated nanocellulose enables efficient CTC capture in head & neck cancer.
20 Sept 2023

Manuscript: Magnetically-activated, nanostructured cellulose for efficient capture of CTCs from the blood sample of head and neck cancer patients

Study compares CNC and CNF cellulose nanostructures for EpCAM-based CTC capture in head and neck cancer, enabling affordable real-time cancer monitoring.

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CTCs in recurrent and metastatic head & neck squamous cell carcinoma.
20 Jul 2023

Manuscript: Role of circulating tumour cells (CTCs) in recurrent/metastatic head and neck squamous cell carcinoma (HNSCC)

This study highlights the utility of CTCs as a disease progression monitoring tool in recurrent HNSCC patients. Our findings suggest the potential clinical utility of CTCs and the need for further exploration in upfront settings of the disease as well (NCT: CTRL/2020/02/023378).

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ASCO 2023 | Actorius Innovations and Research
6 Jun 2023

ASCO 2023: Effect of circulating tumor cells distribution in treatment naive and treated patients with advance stage breast cancer on disease burden.

A study of 417 breast cancer patients shows tracking circulating tumor cells (CTCs) effectively monitors therapy response and recurrence risk.

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ASCO 2023 | Actorius Innovations and Research
6 Jun 2023

ASCO 2023: Circulating tumor cells (CTCs) detection and isolation in different subtypes of early-stage breast cancer patients from Bangladesh.

A trial found CTCs in 60% of early-stage breast cancer patients, notably all HER2-positive cases, linking them to tumor grade. Send the next!

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AACR 2023 | Actorius Innovations and Research
19 Apr 2023

AACR 2023: Detection of PD-L1, HER2 and EGFR on circulating tumor cells in carcinoma patients.

CTC analysis in 134 patients successfully detected PD-L1, HER2, and EGFR, proving its value as a real-time guide for targeted therapies.

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Chemical tunability of advanced materials used in the fabrication of micro/nanobots
11 Apr 2023

Manuscript: Chemical tunability of advanced materials used in the fabrication of micro/nanobots

Review on chemically tunable micro- and nanobots for targeted nanomedicine, highlighting AI materials, applications, and biosafety considerations.

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Economic times  | Actorius Innovations and Research
6 Mar 2023

Pune start-up gets US patent for delivering drugs to site-specific organs

The patent was granted to Actorius Innovations and Research and its team that designed capsule shells using natural polymer to obtain a delayed release profile suitable for delivery of drugs to colon and rectum, said Dr Jayant Khandare, founder-director and Chief Scientific Officer of the start-up.

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AACR 2023 | Actorius Innovations and Research
15 Jan 2023

AACR 2023: Abstract PR007: Comprehensive ctDNA profiling reveals potential metastatic genomic signatures in treatment-naive early-stage breast cancer patients

Comprehensive ctDNA profiling and CTC analysis in early-stage breast cancer identifies driver mutations to predict early metastasis.

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Dr. Jayant Khandare interview with Metro News Gujarat
9 Aug 2022

Revolutionary OncoDiscover® Blood Test for Early Cancer Detection - Metro News Gujarat

Dr. Jayant Khandare interview with Metro News Gujarat

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