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Research That Shapes the Future of Oncology

Access studies, scientific papers, and published findings advancing cancer diagnostics and care.

Real-Time Therapy Response Monitoring Using Surface Biomarkers on Circulating Tumor Cells
27 Jan 2026

Manuscript: Real-Time Therapy Response Monitoring Using Surface Biomarkers on Circulating Tumor Cells

Circulating tumor cells (CTCs), cancer cells shed from primary tumors into the bloodstream, are emerging as dynamic, non-invasive biomarkers for real-time cancer monitoring, especially when tissue biopsies are inaccessible or inadequate...

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TSG mutations predict early relapse in mEGFR lung adenocarcinoma.
14 Mar 2025

Manuscript: The impact of co-occurring tumor suppressor mutations with mEGFR as early indicators of relapse in lung cancer

A set of 17 co-occurring TSG mutations has been identified as key biomarkers for early relapse in mEGFR
lung adenocarcinoma. Longitudinal genomic monitoring, with a focus on clonal evolution, offers valuable insights that can inform personalized treatment strategies and potentially improve patient outcomes.

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Inverse 3D lab-on-chip microfilms for selective CTC capture from blood.
15 Jul 2024

Manuscript: Inverse 3D ‘lab-on-a-chip’ polymeric microfilms for selective capture of circulating tumor cells from patients' blood

Inverse 3D lab-on-chip microfilms for selective CTC capture from blood.

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CTCs as biomarkers for relapse detection in rectal cancer with liver metastasis.
29 Jun 2024

Manuscript: Circulating Tumor Cells as Biomarkers for Relapse Detection in Rectal Cancer with Liver Metastasis: Insights from a Case Report

In this case report we demonstrate the utility of CTC as a sensitive marker to detect MRD. CTCs play a crucial role in the context of MRD in colorectal cancer, offering a valuable biomarker for prognosis, treatment monitoring, and early detection of recurrence.

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CTC together with Shh and Nrf2 are prospective diagnostic markers for HNSCC
4 Apr 2024

Manuscript: CTC together with Shh and Nrf2 are prospective diagnostic markers for HNSCC

Study links Shh/Nrf2 overexpression with circulating tumor cells in HNSCC, highlighting their potential as biomarkers for early detection and survival prediction.

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Magnetically activated nanocellulose enables efficient CTC capture in head & neck cancer.
20 Sept 2023

Manuscript: Magnetically-activated, nanostructured cellulose for efficient capture of CTCs from the blood sample of head and neck cancer patients

Study compares CNC and CNF cellulose nanostructures for EpCAM-based CTC capture in head and neck cancer, enabling affordable real-time cancer monitoring.

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CTCs in recurrent and metastatic head & neck squamous cell carcinoma.
20 Jul 2023

Manuscript: Role of circulating tumour cells (CTCs) in recurrent/metastatic head and neck squamous cell carcinoma (HNSCC)

This study highlights the utility of CTCs as a disease progression monitoring tool in recurrent HNSCC patients. Our findings suggest the potential clinical utility of CTCs and the need for further exploration in upfront settings of the disease as well (NCT: CTRL/2020/02/023378).

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Chemical tunability of advanced materials used in the fabrication of micro/nanobots
11 Apr 2023

Manuscript: Chemical tunability of advanced materials used in the fabrication of micro/nanobots

Review on chemically tunable micro- and nanobots for targeted nanomedicine, highlighting AI materials, applications, and biosafety considerations.

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Preoperative CTC levels predict prognosis and survival in oral squamous cell carcinoma.
1 Jul 2022

Manuscript: Circulating tumor cells as a predictor for poor prognostic factors and overall survival in treatment nay¨ve oral squamous cell carcinoma patients

Preoperative circulating tumor cell levels strongly correlate with metastasis, disease severity, and reduced survival in oral squamous cell carcinoma patients.

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Bioinspired Materials for Wearable Devices and Point-of-Care Testing of Cancer
27 Apr 2022

Manuscript: Bioinspired Materials for Wearable Devices and Point-of-Care Testing of Cancer

Raj Shankar Hazra, Md Rakib Hasan Khan, Narendra Kale, Tabassum Tanha, Jayant Khandare, Sabha Ganai, and Mohiuddin Quadir*

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Antibody-coated cotton substrate for CTC enumeration and chemotherapy response.
18 Feb 2022

Manuscript: Antibody mediated cotton-archetypal substrate for enumeration of circulating tumor cells and chemotherapy outcome in 3D tumors

Cotton microfluidic substrate enables efficient CTC isolation, 3D tumor growth, and drug response testing for improved cancer diagnostics and therapy research.

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Chemo-specific designs for the enumeration of CTCs: advances in liquid biopsy
18 Dec 2020

Manuscript: Chemo-specific designs for the enumeration of circulating tumor cells: advances in liquid biopsy

Review on chemo-specific nano/micro substrates for efficient CTC isolation, enabling liquid biopsy, metastasis detection, and real-time cancer monitoring.

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Cellulose-based transferrin nanocages for CTC enumeration in head & neck cancer.
10 Oct 2020

Manuscript: Cellulose Mediated Transferrin Nanocages for Enumeration of Circulating Tumor Cells for Head
and Neck Cancer

Magnetic transferrin-functionalized cellulose nanocages capture circulating tumor cells from blood, enabling liquid biopsy for early metastasis detection in head and neck cancer.

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Magnetic nanogels enable optimized capture of circulating tumor cells from blood.
11 Feb 2018

Manuscript: Optimizing Circulating Tumor Cells’ Capture Efficiency of Magnetic Nanogels by Transferrin Decoration

Magnetic nanogels with optimized PEG–transferrin linkers achieve over 80% efficiency in selectively capturing circulating tumor cells from blood.

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Micropatterned surfaces enable selective cancer cell capture and real-time monitoring.
17 Jan 2018

Manuscript: Selective Cell Isolation by Transferrin Functionalized Silane– Carbon Soot Mediated Superhydrophobic Micropatterns

Transferrin-functionalized wettability micropatterns enable selective cancer cell capture and real-time monitoring for diagnostics and recurrence detection.

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Biofunctionalized capillary platform with 3D matrix for efficient CTC capture.
17 Jan 2017

Manuscript: Biofunctionalized Capillary Flow Channel Platform Integrated with 3D Nanostructured Matrix to Capture Circulating Tumor Cells

Continuous-flow 3D microchannel platform captures circulating tumor cells with ~90% efficiency, enabling liquid biopsy and real-time cancer monitoring.

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CaP-crowned CNT nanocapsules enable pH-triggered intracellular anticancer drug delivery.
17 Apr 2015

Manuscript:Calcium phosphate nanocapsule crowned multiwalled carbon nanotubes for pH triggered intracellular anticancer drug release

Calcium phosphate–capped carbon nanotubes enable pH-triggered intracellular release of doxorubicin, preventing premature drug leakage and improving targeted cancer therapy.

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Self-propelled CNT microrockets enable rapid capture and isolation of CTCs.
13 Apr 2015

Manuscript: Self-propelled Carbon Nanotube Based Microrockets for Rapid Capture and Isolation of Circulating Tumor Cells

Self-propelled CNT microrockets rapidly capture and magnetically isolate circulating tumor cells, enabling faster liquid biopsy and early cancer detection.

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