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Latest from Actorius

Explore the latest updates, research perspectives, announcements, and stories shaping our work.

ESMO MAP | Actorius Innovations and Research
16 September 2025
Publications

Profiling of PD-L1 and HER2 over expression on cancer cells using AI based macro-driven automation

AI-based image analysis rapidly profiles circulating tumor cells, quantifying morphology and biomarkers like PD-L1 and HER2 for cancer research.

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ASCO 2025 | Actorius Innovations and Research
3 June 2025
Publications

PD-L1 expression on circulating tumor cells and CTC clusters as a minimal cellular disease in breast cancer patients.

This breast cancer study shows high prevalence of PD-L1–positive circulating tumor cells, supporting their role in minimal residual disease and metastasis risk.

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ASCO 2025 | Actorius Innovations and Research
3 June 2025
Publications

Circulating tumor cells and clusters exhibiting expression of PD-L1 in colorectal patients.

High prevalence of PD-L1–positive circulating tumor cells in colorectal cancer highlights their role in minimal residual disease and recurrence monitoring.

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ASCO 2025 | Actorius Innovations and Research
3 June 2025
Publications

Use of dynamic blood flow device with conjugated affinity ligands on glass substrate to capture circulating tumor cells in cancer patients.

Continuous-flow 3D glass substrate device safely captures circulating tumor cells, demonstrating potential to reduce metastasis and improve cancer survival.

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ASCO 2025 | Actorius Innovations and Research
3 June 2025
Publications

Quadrant of co-occurrence of circulating tumor DNA and PD-L1 expression on circulating tumor cells in monitoring disease aggressiveness and metastasis in lung cancer.

Combined ctDNA and PD-L1–positive CTC analysis improves monitoring of metastasis, minimal residual disease, and treatment response in lung cancer.

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CTC and PD-L1 profiling across cancers supports monitoring, recurrence detection, and MRD.
3 June 2025
Publications

Comparative analysis of circulating tumor cell distribution with PD-L1 expression in baseline and follow ups patients across cancer types.

This multi-cancer study shows CTC and PD-L1 prevalence across Indian patients, supporting minimal residual disease monitoring and personalized cancer care.

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ISMRC Symposium | Actorius Innovations and Research
9 May 2025
Publications

Accounts of circulating tumor cells and CTC clusters with PD-L1 expression in sarcoma patients

Study shows circulating tumor cells with PD-L1 expression and clusters in sarcoma, indicating minimal residual disease and need for long-term monitoring.

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TSG mutations predict early relapse in mEGFR lung adenocarcinoma.
14 March 2025
Manuscript

Manuscript: The impact of co-occurring tumor suppressor mutations with mEGFR as early indicators of relapse in lung cancer

A set of 17 co-occurring TSG mutations has been identified as key biomarkers for early relapse in mEGFR
lung adenocarcinoma. Longitudinal genomic monitoring, with a focus on clonal evolution, offers valuable insights that can inform personalized treatment strategies and potentially improve patient outcomes.

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ISLB 2024 | Actorius Innovations and Research
25 November 2024
Publications

ISLB 2024: Transit of Circulating Tumor Cells (CTC) Post Radiotherapy at Irradiated Tumor Regions in Pan-cancer Patients

Study links radiotherapy exposure with circulating tumor cells and PD-L1 expression, indicating possible minimal residual disease and metastatic risk.

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ISLB 2024 | Actorius Innovations and Research
25 November 2024
Publications

ISLB 2024: Comprehensive Analysis of ctDNA and CTCs Reveals Resistance signatures and Correlations with PET Scan Outcomes in Cancer Patients

Integrated ctDNA and CTC analysis correlates with PET-CT outcomes to reveal treatment resistance and aggressive cancer progression.

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ISLB 2024 | Actorius Innovations and Research
25 November 2024
Publications

ISLB 2024: Expression of Programmed Death - Ligand 1 as a dynamic biomarker on circulating tumor cells in pancreatic cancer patients

CTC detection with PD-L1 overexpression reveals aggressive pancreatic cancer and potential biomarker value for monitoring metastasis and disease progression.

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ESMO 2024 | Actorius Innovations and Research
17 September 2024
Publications

ESMO 2024: True single-circulating tumor cell genomics reveals enriched therapy-resistance signatures in advanced colorectal cancer patients

Single CTC genomics reveals actionable mutations and therapy resistance signatures not detected in paired ctDNA in advanced colorectal cancer.

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Inverse 3D lab-on-chip microfilms for selective CTC capture from blood.
15 July 2024
Manuscript

Manuscript: Inverse 3D ‘lab-on-a-chip’ polymeric microfilms for selective capture of circulating tumor cells from patients' blood

Inverse 3D lab-on-chip microfilms for selective CTC capture from blood.

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CTCs as biomarkers for relapse detection in rectal cancer with liver metastasis.
29 June 2024
Manuscript

Manuscript: Circulating Tumor Cells as Biomarkers for Relapse Detection in Rectal Cancer with Liver Metastasis: Insights from a Case Report

In this case report we demonstrate the utility of CTC as a sensitive marker to detect MRD. CTCs play a crucial role in the context of MRD in colorectal cancer, offering a valuable biomarker for prognosis, treatment monitoring, and early detection of recurrence.

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ASCO 2024 | Actorius Innovations and Research
4 June 2024
Publications

ASCO 2024: Effect of circulating tumor cells in clinically stable patients on the conundrum of recurrence with cellular residual disease.

CTC detection with PD-L1 expression reveals residual disease despite negative radiological findings in treated cancer patients.

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ASCO 2024 | Actorius Innovations and Research
3 June 2024
Publications

ASCO 2024: Effect of circulating tumor cells (CTC) and CTC clusters with PD-L1 dynamic biomarker on cellular burden in patients with ovarian cancer.

CTCs with PD-L1 expression in ovarian cancer reveal minimal residual disease and may guide immunotherapy and early metastasis monitoring.

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ASCO 2024 | Actorius Innovations and Research
3 June 2024
Publications

ASCO 2024: Measure of minimal residual burden on CTCs with over-expression of PD-L1 as a dynamic biomarker in patients with colorectal cancer.

CTC detection with PD-L1 expression in colorectal cancer reveals minimal residual disease and supports personalized treatment strategies.

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ASCO 2024 | Actorius Innovations and Research
3 June 2024
Publications

ASCO 2024: Impact of ctDNA genomic mutations and CTCs biomarker duo on clinical concordance in localized, progressive, and metastatic disease.

Dual biomarker analysis of ctDNA and circulating tumor cells reveals disease progression and metastasis across multiple cancer types.

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ASCO 2024 | Actorius Innovations and Research
3 June 2024
Publications

ASCO 2024: Association of complementing ctDNA and CTCs load on stable and progressive disease in treated patients.

Complementary ctDNA and CTC biomarkers reveal minimal residual disease and predict cancer progression after curative-intent treatment.

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Nature India | Actorius Innovations and Research
11 April 2024
Press Release

Magnetic nanocrystals capture tumour cells from blood samples

These nanomaterials could speed up discovery of anti-cancer drugs

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